MyBioSource.com's Anti-Hsp40 (Ydj1) Monoclonal Antibody is a Mouse monoclonal antibody. This antibody has been shown to work in applications such as: ELISA, Immunoprecipitation, and Western Blot.
Description
Members of the human Hsp40/DnaJ protein family feature a J domain (named for the bacterial DnaJ protein). The J domain spans the first 75 N-terminal amino acids and is separated from the C-terminus by a glycine-phenylalanine-rech domain. The Hsp40/DnaJ proteins play many different roles in cellular processes such as folding, translocation, degradation, and assembly of multi-protein complexes. Hdj1, the first human Hsp40/DnaJ protein identified, plays an important role in protein translation and folding as well as in regulation of Hsp70 function. Hsp40 stimulates ATPase activity of Hsp70 which in turn causes conformational changes in unfolded proteins